Isolation and Identification of Anticoagulant Components from the Venom of Honey Bee (Apis Mellifera Caucasica)
نویسندگان
چکیده
منابع مشابه
Isolation and Identification of Biologically Active Components from the Honey Bee Venom Apis Mellifera L. Caucasica
The venom of the European honey bee Apis mellifera is an intricate mixture of chemical compositions, including proteins, peptides, enzymes, and other small molecules. Lately, there has been growing interest in the use of melittin, due to its wide range of biological and potential therapeutic applications. Melittin, which is considered to be an antimicrobial, antitumor, and antiinflammatory pept...
متن کاملEffect of Honey Bee Venom (Apis mellifera) on Hyperglycemia and Hyperlipidemia in Alloxan Induced Diabetic Rabbits
Introduction: In diabetes therapy, a great attention is paid on lowering blood glucose levels and lipid regulating mechanisms of various medical agents including animal toxins. Honey bee venom reduces blood glucose level through increased insulin secretion and glucose take-up. It also has lipid regulating activity verified in several other studies. For that reason, bee venom could be considered...
متن کاملEffect of Iranian Honey bee (Apis mellifera) Venom on Blood Glucose and Insulin in Diabetic Rats
BACKGROUND Diabetes is an important disease. This disease is a metabolic disorder characterized by hyperglycemia resulting from perturbation in insulin secretion, insulin action or both. Honey bee venom contains a wide range of polypeptide agents. The principle components of bee venom are mellitin and phospholipase A(2). These components increase insulin secretion from the β-cells of pancreas. ...
متن کاملHoney Bee Venom (Apis mellifera) Contains Anticoagulation Factors and Increases the Blood-clotting Time.
OBJECTIVES Bee venom (BV) is a complex mixture of proteins and contains proteins such as phospholipase and melittin, which have an effect on blood clotting and blood clots. The mechanism of action of honey bee venom (HBV, Apis mellifera) on human plasma proteins and its anti-thrombotic effect were studied. The purpose of this study was to investigate the anti-coagulation effect of BV and its ef...
متن کاملOxidative Enzyme Systems of the Honey Bee, Apis Mellifera L
1. Oxidative dissimilation has been studied in enzymes from the honey bee. Using mitochondria isolated from the thoraces, complete oxidation of most of the TCA cycle members has been shown. 2. The presence of the acetate-activating enzyme, citrate-condensing enzyme, isocitric dehydrogenase, alpha-ketoglutarate dehydrogenase, glucose-6-phosphate, and 6-phosphogluconic dehydrogenase has been demo...
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ژورنال
عنوان ژورنال: MOJ Biology and Medicine
سال: 2017
ISSN: 2574-9722
DOI: 10.15406/mojbm.2017.01.00032